Tankwa Karoo National Park is a national park in South Africa.
The park lies about 70 km due west of Sutherland near the border of the Northern Cape and Western Cape, in one of the most arid regions of South Africa, with areas receiving less than 100 mm of average annual precipitation, moisture-bearing clouds from the Atlantic Ocean being largely stopped by the Cederberg mountains. Other low areas receive little more, as the Roodewerf station (co-ordinates: S32°14’27.9” E20°05’44.5”) with 180 mm of mean annual rainfall. In the hottest areas of the park, the mean maximum temperature in January is 38.9 °C, and in July the mean minimum temperature ranges from about 5 to 7 °C.
Before this Park’s proclamation, the only protected area of Succulent Karoo was the 2 square kilometre patch of the Gamkaberg Nature Reserve. Succulent Karoo has, together with the Cape Floral Kingdom, been declared a Biodiversity Hotspot by Conservation International.